Facultad de Agronomia - UBA

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Acceso al documento : Documento de Acceso Libre
URL al registro : http://ri.agro.uba.ar/cgi-bin/library.cgi?a=d&c=arti&d=2018martini
Tipo de material : Artículo
Autores : Martini, Johannes W. R.; Schrauf, Matías Florián; García Baccino, Carolina Andrea; Pimentel, Eduardo C. G.; Munilla Leguizamón, Sebastián; Rogberg Muñoz, Andrés; Cantet, Rodolfo Juan Carlos; Reimer, Christian; Gao, Ning; Wimmer, Valentin; Simianer, Henner
Título en inglés : The effect of the H−1 scaling factors t and w on the structure of H in the single‑step procedure
Fuente : Genetics selection evolution
Año : 2018
Volumen y número : Vol.50
Idioma : inglés
Descripción : grafs.
Páginas :  9 p.
Resumen : Background: The single-step covariance matrix H combines the pedigree-based relationship matrix A with the more accurate information on realized relatedness of genotyped individuals represented by the genomic relationship matrix G. In particular, to improve convergence behavior of iterative approaches and to reduce inflation, two weights t and w have been introduced in the definition of H−1, which blend the inverse of a part of A with the inverse of G. Since the definition of this blending is based on the equation describing H−1, its impact on the structure of H is not obvious. In a joint discussion, we considered the question of the shape of H for non-trivial t and w. Results: Here, we present the general matrix H as a function of these parameters and discuss its structure and properties. Moreover, we screen for optimal values of t and w with respect to predictive ability, inflation and iterations up to convergence on a well investigated, publicly available wheat data set. Conclusion: Our results may help the reader to develop a better understanding for the effects of changes of t and w on the covariance model. In particular, we give theoretical arguments that as a general tendency, inflation will be reduced by increasing t or by decreasing w.
DOI : 10.1186/s12711-018-0386-x
Link al editor : https://www.biomedcentral.com/
Cita recomendada : Martini, J. W. R.; Schrauf, M. F.; García Baccino, C. A.; Pimentel, E. C. G.; Munilla Leguizamón, S.; Rogberg Muñoz, A.;... Simianer, H. (2018). The effect of the H−1 scaling factors t and w on the structure of H in the single‑step procedure. Genetics selection evolution‚ 50‚ (16) 9 p.. Doi: 10.1186/s12711-018-0386-x.